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Oral administration allows for easy daily use without the discomfort, complexity or potential side effects associated with injections

For oral supplementation in individuals with adequate absorption capacity, serum B12 levels typically begin rising within one to two weeks of starting treatment

These compounds may have deviations from the brand name substitute

According to SUCRA values, the top two ranked administration routes were the oral route (78.3) followed by the IM route (49.6) (Table 3(B))

Pregnancy recommendation: compatible

Eligible studies included randomised controlled trials, cohort, and case-control studies assessing B12 supplementation efficacy via oral, sublingual, or IM administration routes